For a while in the 90's I was working for a novelty toy prototyping company, churning out resin castings to make tooling and paint masters for production. I couldn't tell you what resin and silicon to use, as I'm sure it's all moved on, but I reckon the use of a vacuum chamber hasn't. It is in my view the only way to make reliable tools at those kinds of sizes, then to produce reliable castings.
Of course things may have moved on again, but I'm fairly sure you still need to remove the bubbles.
You may have one already, in which case "I'll get me coat..."
Tony